Antihypertensive therapy and orthostatic hemodynamic responses in acute stroke

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Antihypertensive therapy and orthostatic hemodynamic responses in acute stroke.

BACKGROUND It is not known whether antihypertensive medications affect orthostatic blood pressure (BP) regulation in the early period after stroke. Knowledge of this may have implications for clinical practice. METHODS A total of 40 acute ischemic stroke patients (mild-to-moderate severity) taking antihypertensive drugs, and 40 patients with acute stroke of similar severity not receiving such...

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Orthostatic haemodynamic responses in acute stroke.

Little is known about orthostatic blood pressure regulation in acute stroke. We determined postural haemodynamic responses in 40 patients with acute stroke (mild or moderate severity) and 40 non-stroke control in-patients, at two days ('Day 1') and one week ('Week 1') post-admission. Following a 10-minute supine rest and baseline readings, subjects sat up and blood pressure and heart rate were ...

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Hemodynamic and reflex responses to acute and chronic antihypertensive therapy with the calcium entry blocker nifedipine.

Calcium entry blockers are potent vasodilators and may be suitable for antihypertensive therapy. We investigated hemodynamic responses together with changes of plasma catecholamines and renin activity (PRA) in 11 men (38.2 ±5 .1 years) with essential hypertension (EHT, WHO I—II) after administration of nifedipine 10 mg sublingually (s.l.) and after 6 weeks treatment with nifedipine 20 mg three ...

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Antihypertensive therapy in acute ischemic stroke: Lost in the mist

The results of the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS) study were presented last month at the 2013 American Heart Association Scientific Meeting and simultaneously published in the Journal of the American Medical Association [1]. The CATIS study was a multicenter, controlled, randomized study that aimed to assess the effects of blood pressure reduction during the acute...

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ژورنال

عنوان ژورنال: American Journal of Hypertension

سال: 2002

ISSN: 0895-7061,1941-7225

DOI: 10.1016/s0895-7061(01)02253-1